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Reviewing written physiciannotes on 118 subjects with loss of consciousness, physi-cians came to the appropriate diagnosis in less than athird of all patients. This approach can be varied to allow better assess-ment of atypical analytes. When cases were strati?ed according to p53 status and Pin1 expression levels,overall survival was found to be signi?cantly decreased in patients with tumorsexpressing high levels of Pin1 and p53 missense mutations, compared to cases with lowPin1 expression and p53 missense mutations, or cases bearing wild-type p53 [ 11 ].In addition, p53 mutation correlates with shorter OS only in cases with high Pin1expression levels.
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